DNA-designed avian IgY antibodies: novel tools for research, diagnostics and therapy
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Can egg yolk antibodies terminate the CSBV infection in apiculture?
2023, Virus ResearchStructure and evolution of avian immunoglobulins
2021, Avian ImmunologyThe protective efficacy of specific egg yolk immunoglobulin Y(IgY) against Riemerella Anatipestifer infections
2020, Veterinary MicrobiologyCitation Excerpt :IgY is recognized as an excellent source of polyclonal antibodies, and has attracted significant attention as a potential method for preventing and controlling diseases due to its high specificity, as IgY is considered easy to work and inexpensive, and reports have identified it as a promising alternative to antibiotics as a new candidate for passive immunization (Hong et al., 2018). Furthermore, IgY can be obtained through a simple and economic process of isolation, with over 60−100 mg of purified IgY able to be obtained from a single egg (Cova, 2005). IgY may be produced in large yields, and production is scalable (Schade et al., 2005).
Antiparasitic effects induced by polyclonal IgY antibodies anti-phospholipase A<inf>2</inf> from Bothrops pauloensis venom
2018, International Journal of Biological MacromoleculesCitation Excerpt :Chicken eggs immunized with different antigens represent an excellent source of polyclonal IgY antibodies, which have been widely used as a biotechnological tool for immunotherapy, diagnostic application and neutralization of ophidian venoms [50,51]. In addition, they have advantages over production in mammals, such as lower production costs, higher yields and better ethical aspects [52–54]. The PLA2s present in eukaryotic and prokaryotic organisms are described as participating in several cellular processes, such as invasion and penetration into host cells, membrane remodeling and generation of lipid messengers.
Highly sensitive detection of cancer antigen human epidermal growth factor receptor 2 using novel chicken egg yolk immunoglobulin
2015, BiologicalsCitation Excerpt :Eggs can be collected daily from the same hen and processed either individually or, as desired, from hens belonging to a similar immunized group. Over 100 mg of purified IgY can be obtained from a single egg [19]. As hens continue producing eggs along at least 10 months, it is possible to obtain enormous amounts of specific IgY directed to the same or related antigens [20].