Journal of Clinical Virology
Volume 44, Issue 2 , Pages 145-148 , February 2009

Clinical and molecular characteristics of hepatitis A virus infections during the years 1992–2003 in Ogaki, a centrally located city of Japan

  • Hidenori Toyoda

      Affiliations

    • Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Manaminokawa, Ogaki, Gifu 503-8502 Japan
    • ,
  • Takashi Kumada

      Affiliations

    • Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Manaminokawa, Ogaki, Gifu 503-8502 Japan
    • ,
  • Seiki Kiriyama

      Affiliations

    • Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Manaminokawa, Ogaki, Gifu 503-8502 Japan
    • ,
  • Yasuhiro Sone

      Affiliations

    • Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Manaminokawa, Ogaki, Gifu 503-8502 Japan
    • ,
  • Makoto Tanikawa

      Affiliations

    • Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Manaminokawa, Ogaki, Gifu 503-8502 Japan
    • ,
  • Yasuhiro Hisanaga

      Affiliations

    • Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Manaminokawa, Ogaki, Gifu 503-8502 Japan
    • ,
  • Akira Kanamori

      Affiliations

    • Department of Gastroenterology, Ogaki Municipal Hospital, 4-86 Manaminokawa, Ogaki, Gifu 503-8502 Japan
    • ,
  • Chiung-Ling Lin

      Affiliations

    • Department of Medical Research, Mackay Memorial Hospital, 45 Min-Sheng Rd., Tamshui, 25160 Taipei, Taiwan
    • ,
  • Hsin-Fu Liu

      Affiliations

    • Department of Medical Research, Mackay Memorial Hospital, 45 Min-Sheng Rd., Tamshui, 25160 Taipei, Taiwan
    • Department of General Education, National Taipei College of Nursing, Taipei, Taiwan
    • Corresponding Author InformationCorresponding author. Tel.: +886 2 2809 4661x2073; fax: +886 2 2808 5952.

Received 12 September 2008 ,Revised 12 November 2008 ,Accepted 2 December 2008.

References 

  1. World Health Organisation. Hepatitis A vaccines. Wkly Epidemiol Rec. 2000; 75:38–44.
  2. Hussain Z, Das BC, Husain SA, Asim M, Chattopadhyay S, Malik A, et al. Hepatitis A viral genotypes and clinical relevance: clinical and molecular characterization of hepatitis A virus isolates from northern India. Hepatol Res. 2005;32:16–24
  3. Chironna M, Grottola A, Lanave C, Villa E, Barbuti S, Quarto M. Genetic analysis of HAV strains recovered from patients with acute hepatitis from Southern Italy. J Med Virol. 2003;70:343–349
  4. Cuthbert JA. Hepatitis A: old and new. Clin Microbiol Rev. 2001;14:38–58
  5. Hutin YJF, Pool V, Cramer EH, Nainan OV, Weth J, Williams IT, et al. A multistate, foodborne outbreak of hepatitis A. N Engl J Med. 1999;340:595–602
  6. Sanchez G, Pinto RM, Vanaclocha H, Bosch A. Molecular characterization of hepatitis A virus isolates from a transcontinental shellfish-borne outbreak. J Clin Microbiol. 2002;40:4148–4155
  7. Tamura K, Dudley J, Nei M, Kumar S. MEGA4: molecular evolutionary genetic analysis (MEGA) software version 4.0. Mol Biol Evol. 2007;24:1596–1599
  8. Felsenstein J. Mathematics vs. evolution: mathematical evolutionary theory. Science. 1989;246:941–942
  9. Kiyohara T, Satoh T, Yamamoto H, Totsuka A, Moritsugu Y. The latest seroepidemiological pattern of hepatitis A in Japan. Jpn J Med Sci Biol. 1997;50:123–131
  10. Takahashi H, Yotsuyanagi H, Yasuda K, Koibuchi T, Suzuki M, Kato T, et al. Molecular epidemiology of hepatitis A virus in metropolitan areas in Japan. J Gastroenterol. 2006;41:981–986
  11. Yun H, Kim S, Lee H, Byun KS, Kwon SY, Yim HJ, et al. Genetic analysis of HAV strains isolated from patients with acute hepatitis in Korea, 2005–2006. J Med Virol. 2008;80:777–784
  12. Tjon GMS, Wijkmans CJ, Coutinho RA, Koek AG, van den Hoek JAR, Leenders ACAP, et al. Molecular epidemiology of hepatitis A in Noord-Brabant, the Netherlands. J Clin Virol. 2005;32:128–136

☆ The nucleotide sequence data reported in this paper will appear in the GenBank nucleotide sequence databases with the accession numbers FJ445783–FJ445855. This study was funded in part by Mackay Memorial Hospital (grant MMH 9559).

PII: S1386-6532(08)00426-5

doi: 10.1016/j.jcv.2008.12.002

Journal of Clinical Virology
Volume 44, Issue 2 , Pages 145-148 , February 2009

Article Tools

* Image Usage & Resolution