Journal of Clinical Virology
Volume 45, Issue 3 , Pages 191-195 , July 2009

Evaluation of multiple test methods for the detection of the novel 2009 influenza A (H1N1) during the New York City outbreak

  • Christine C. Ginocchio

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
    • Corresponding Author InformationCorresponding author at: North Shore-LIJ Health System Laboratories, 10 Nevada Drive, Lake Success, NY 11042, United States. Tel.: +1 516 719 1079; fax: +1 516 719 1254.
  • ,
  • Frank Zhang

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • Ryhana Manji

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • Suman Arora

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • Mark Bornfreund

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • Leon Falk

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • Madhavi Lotlikar

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • Margaret Kowerska

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • George Becker

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • Diamanto Korologos

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • Marcella de Geronimo

      Affiliations

    • Krasnoff Quality Management Institute, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States
  • ,
  • James M. Crawford

      Affiliations

    • Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, Lake Success, NY 11042, United States

Received 3 June 2009 ,Accepted 5 June 2009.

References 

  1. Centers for Disease Control and Prevention. CDC protocol of real time RTPCR for influenza A (H1N1). April 2009. www.who.int/csr/resources/publications/swineflu/realtimeptpcr/en/index.html.
  2. Centers for Disease Control and Prevention . Outbreak of swine-origin influenza A (H1N1) virus infection – Mexico, March–April 2009. MMWR Morb Mortal Wkly Rep. 2009;58(May 8 (17)):467–470
  3. Centers for Disease Control and Prevention . Swine-origin Influenza A (H1N1) virus infections in a school – New York City, May 2009. MMWR Morb Mortal Wkly Rep. 2009;May 8 (58)(17):470–472
  4. Ginocchio CC, Lotlikar M, Falk L, Arora S, Kowerska M, Bornfreund M, et al. Clinical performance of the 3M Rapid Detection Flu A+B test compared to R-Mix culture, DFA and BinaxNOW A&B test. J Clin Virol. 2009;45:146–149
  5. Ginocchio CC, St. George K. Likelihood that an unsubtypeable influenza A result in the Luminex xTAG Respiratory Virus Panel is indicative of novel H1N1 (swine-like) influenza. J Clin Microbiol, 2009 June 3 [Epub ahead of print].
  6. Krunic N, Yager TD, Himsworth D, Merante F, Yaghoubian S, Janeczko R. xTAG RVP assay: analytical and clinical performance. J Clin Virol. 2007;40(Suppl. 1):S39–S46
  7. Leland D, Ginocchio CC. Role of cell culture for virus detection in the age of technology. Clin Microbiol Rev. 2007;20:49–78
  8. Mahony J, Chong S, Merante F, Yaghoubian S, Sinha T, Lisle C, et al. Development of a Respiratory Virus Panel test for detection of twenty human respiratory viruses by use of multiplex PCR and a fluid microbead-based assay. J Clin Microbiol. 2007;45:2965–2970
  9. Merante F, Yaghoubian S, Janeczko R. Principles of the xTAG respiratory viral panel assay (RVP assay). J Clin Virol. 2007;40(Suppl. 1):S31–35

PII: S1386-6532(09)00254-6

doi: 10.1016/j.jcv.2009.06.005

Journal of Clinical Virology
Volume 45, Issue 3 , Pages 191-195 , July 2009