Journal of Clinical Virology
Volume 46, Issue 4 , Pages 360-362 , December 2009

Hepatic steatosis is uncommon in children with chronic hepatitis B

  • Antonietta Giannattasio

      Affiliations

    • Department of Pediatrics, University “Federico II”, Naples, Italy
    • ,
  • Francesco Cirillo

      Affiliations

    • Department of Pediatrics, University “Federico II”, Naples, Italy
    • ,
  • Vito Terlizzi

      Affiliations

    • Department of Pediatrics, University “Federico II”, Naples, Italy
    • ,
  • Daniela Liccardo

      Affiliations

    • Department of Pediatrics, University “Federico II”, Naples, Italy
    • ,
  • Raffaella Vecchione

      Affiliations

    • Department of Biomorphological Science, University “Federico II”, Naples, Italy
    • ,
  • Raffaele Iorio

      Affiliations

    • Department of Pediatrics, University “Federico II”, Naples, Italy
    • Corresponding Author InformationCorresponding author at: Department of Pediatrics, University “Federico II”, Via S. Pansini 5, 80131, Naples, Italy. Tel.: +39 0817464337; fax: +39 0817464337.

Received 9 July 2009 ,Revised 15 September 2009 ,Accepted 15 September 2009.

References 

  1. Schwimmer JB, Deutsch R, Kahen T, Lavine JE, Stanley C, Behling C. Prevalence of fatty liver in children and adolescents. Pediatrics. 2006;118:1388–1393
  2. Hwang SJ, Luo JC, Chu CW, Lai CR, Lu CL, Tsay SH, et al. Hepatic steatosis in chronic hepatitis C virus infection: prevalence and clinical correlation. J Gastroenterol Hepatol. 2001;16:190–195
  3. Giannattasio A, Spagnuolo MI, Sepe A, Valerio G, Vecchione R, Vegnente A, et al. Is HCV infection associated with liver steatosis also in children?. J Hepatol. 2006;45:350–354
  4. Guido M, Bortolotti F, Jara P, Giacomelli L, Fassan M, Hierro L, et al. Liver steatosis in children with chronic hepatitis C. Am J Gastroenterol. 2006;101:2616–2618
  5. Adinolfi LE, Gambardella M, Andreana A, Tripodi MF, Utili R, Ruggiero G. Steatosis accelerates the progression of liver damage of chronic hepatitis C patients and correlates with specific HCV genotype and visceral obesity. Hepatology. 2001;33:1358–1364
  6. Thomopoulos KC, Arvaniti V, Tsamantas AC, Dimitropoulou D, Gogos CA, Siagris D, et al. Prevalence of liver steatosis in patients with chronic hepatitis B: a study of associated factors and of relationship with fibrosis. Eur J Gastroenterol Hepatol. 2006;18:233–237
  7. Gordon A, McLean CA, Pedersen JS, Bailey MJ, Roberts SK. Hepatic steatosis in chronic hepatitis B and C: predictors, distribution and effect on fibrosis. J Hepatol. 2005;43:38–44
  8. Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, Flegal KM, Guo SS, Wei R, et al. CDC growth charts: United States. Adv Data. 2000;8:1–27
  9. Poskitt EM. Defining childhood obesity: the relative body mass index (BMI). European Childhood Obesity group. Acta Paediatr. 1995;84:961–963
  10. Tanner JM, Whitehouse RH. Clinical longitudinal standards for height, weight, height velocity, weight velocity, and stages of puberty. Arch Dis Child. 1976;51:170–179
  11. Lok AS, McMahon BJ. Chronic hepatitis B. Hepatology. 2001;34:1225–1241
  12. Ishak K, Baptista A, Bianchi L, Callea F, De Groote J, Gudat F, et al. Histological grading and staging of chronic hepatitis. J Hepatol. 1995;22:696–699
  13. Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005;41:1313–1321

PII: S1386-6532(09)00445-4

doi: 10.1016/j.jcv.2009.09.021

Journal of Clinical Virology
Volume 46, Issue 4 , Pages 360-362 , December 2009

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