Journal of Clinical Virology
Volume 47, Issue 1 , Pages 34-37 , January 2010

Evaluation of a rapid molecular algorithm for detection of pandemic influenza A (H1N1) 2009 virus and screening for a key oseltamivir resistance (H275Y) substitution in neuraminidase

  • E. van der Vries

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • M. Jonges

      Affiliations

    • Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
  • ,
  • S. Herfst

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • J. Maaskant

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • A. Van der Linden

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • J. Guldemeester

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • G.I. Aron

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • T.M. Bestebroer

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • M. Koopmans

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    • Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
  • ,
  • A. Meijer

      Affiliations

    • Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
  • ,
  • R.A.M. Fouchier

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • A.D.M.E. Osterhaus

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • C.A. Boucher

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
  • ,
  • M. Schutten

      Affiliations

    • Erasmus MC, Department of Virology, ‘s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    • Corresponding Author InformationCorresponding author. Tel.: +31 10 7034363; fax: +31 10 7033441.

Received 3 August 2009 ,Revised 22 September 2009 ,Accepted 25 September 2009.

References 

  1. WHO. World now at the start of 2009 influenza pandemic, June 11, 2009 http://www.who.int/mediacentre/news/statements/2009/h1n1_pandemic_phase6_20090611/en/index.html; 2009.
  2. Lackenby A, Thompson CI, Democratis J. The potential impact of neuraminidase inhibitor resistant influenza. Curr Opin Infect Dis. 2008;21(December (6)):626–638
  3. Rungrotmongkol T, Intharathep P, Malaisree M, Nunthaboot N, Kaiyawet N, Sompornpisut P, et al. Susceptibility of antiviral drugs against 2009 influenza A (H1N1) virus. Biochem Biophys Res Commun. 2009;385(July (3)):390–394
  4. Hurt AC, Ernest J, Deng YM, Iannello P, Besselaar TG, Birch C, et al. Emergence and spread of oseltamivir-resistant A(H1N1) influenza viruses in Oceania, South East Asia and South Africa. Antiviral Res. 2009;83(July (1)):90–93
  5. de Jong MD, Tran TT, Truong HK, Vo MH, Smith GJ, Nguyen VC, et al. Oseltamivir resistance during treatment of influenza A (H5N1) infection. N Engl J Med. 2005;353(December (25)):2667–2672
  6. Singer AC, Nunn MA, Gould EA, Johnson AC. Potential risks associated with the proposed widespread use of Tamiflu. Environ Health Perspect. 2007;115(January (1)):102–106
  7. Poland GA, Jacobson RM, Ovsyannikova IG. Influenza virus resistance to antiviral agents: a plea for rational use. Clin Infect Dis. 2009;48(May (9)):1254–1256
  8. Zambon M, Hayden FG. Position statement: global neuraminidase inhibitor susceptibility network. Antiviral Res. 2001;49(March (3)):147–156
  9. Bright RA, Shay DK, Shu B, Cox NJ, Klimov AI. Adamantane resistance among influenza A viruses isolated early during the 2005–2006 influenza season in the United States. JAMA. 2006;295(February (8)):891–894
  10. You Y, Moreira BG, Behlke MA, Owczarzy R. Design of LNA probes that improve mismatch discrimination. Nucleic Acids Res. 2006;34(8):e60
  11. de Wit E, Spronken MIJ, Vervaet G, Rimmelzwaan GF, Osterhaus A, Fouchier RAM. A reverse-genetics system for influenza A virus using T7 RNA polymerase. J Gen Virol. 2007;88(April):1281–1287
  12. Hahné S, Donker T, Meijer A, Timen A, van Steenbergen J, Osterhaus A, et al. Epidemiology and control of influenza A(H1N1)v in the Netherlands: the first 115 cases. Euro Surveillance. 2009;14(July (27)):pii=19267
  13. Ward CL, Dempsey MH, Ring CJ, Kempson RE, Zhang L, Gor D, et al. Design and performance testing of quantitative real time PCR assays for influenza A and B viral load measurement. J Clin Virol. 2004;29(March (3)):179–188
  14. Munster VJ, Baas C, Lexmond P, Bestebroer TM, Guldemeester J, Beyer WEP, et al. Practical considerations for high-throughput influenza A virus surveillance studies of wild birds by use of molecular diagnostic tests. J Clin Microbiol. 2009;47(March (3)):666–673
  15. van Doornum GJJ, Schutten M, Voermans J, Guldemeester GJJ, Niesters HGM. Development and implementation of real-time nucleic acid amplification for the detection of enterovirus infections in comparison to rapid culture of various clinical specimens. J Med Virol. 2007;79(October (12)):1868–1876
  16. Koopmans MP, van Gageldonk M, Hahné S, Isken L, de Jong MD, Jonges M, et al. Clinical findings, viral loads, response to therapy, and resistance monitoring in patients with new influenza A(H1N1)v; submitted for publication.

PII: S1386-6532(09)00478-8

doi: 10.1016/j.jcv.2009.09.030

Journal of Clinical Virology
Volume 47, Issue 1 , Pages 34-37 , January 2010